OH grupa nije dobra odlazeća grupa u reakcijama nukleofilne supstitucije, tako da neutralni alkoholi ne reaguju u takvim reakcijama. Međutim, ako se kiseonik prvo protonira i formira R−OH2+, odlazeća grupa (voda) je daleko stabilnija, i nukleofilna supstitucija se može odvijati. Na primer, tercijarni alkoholi reaguju sa hlorovodoničnom kiselinom i proizvode tercijarne alkil halide, pri čemu se hidroksilna grupa zamenjuje atomom hlora putem unimolekularne nukleofilne supstitucije.
employee in ten—so no less than it'd with assurance be believed—is employed on required matters.
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Alcohols could possibly be classified as Main, secondary, or tertiary, In line with which carbon in the alkyl team is bonded towards the hydroxyl group. Most alcohols are colourless liquids or solids at area temperature.
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